Rapid recovery from K current inactivation on membrane hyperpolarization in molluscan neurons.
نویسندگان
چکیده
منابع مشابه
Rapid recovery from K current inactivation on membrane hyperpolarization in molluscan neurons
Recovery from K current inactivation was studied in molluscan neurons using two-microelectrode and internal perfusion voltage clamps. Experiments were designed to study the voltage-dependent delayed outward current (IK) without contamination from other K currents. The amount of recovery from inactivation and the rate of recovery increase dramatically when the membrane potential is made more neg...
متن کاملHyperpolarization in Molluscan Neurons
Recovery from K current inactivation was studied in molluscan neurons using two-microelectrode and internal perfusion voltage clamps . Experiments were designed to study the voltage-dependent delayed outward current (IK) without contamination from other K currents . The amount of recovery from inactivation and the rate ofrecovery increase dramatically when the membrane potential is made more ne...
متن کاملInactivation of voltage-gated delayed potassium current in molluscan neurons. A kinetic model.
Voltage-gated delayed potassium current in molluscan neurons is characterized by a marked inactivation. Inactivation can accumulate between repetitive pulses, giving rise to current patterns in which the maximum current during a second voltage pulse is less than the current at the end of the preceding pulse (cumulative inactivation). Other features of inactivation of this current include an ons...
متن کاملInactivation of delayed outward current in molluscan neurone somata.
1. Inactivation of delayed outward current was studied by voltage clamp of isolated neurone somata of the molluscs Archidoris and Anisodoris. During prolonged voltage clamp steps in normal artificial sea water delayed outward current rises to a peak and then declines to a non-zero steady-state. During repetitive clamp pulses at repetition rates slower than 2/sec, the amplitude of peak outward c...
متن کاملNa+-activated K+ current contributes to postexcitatory hyperpolarization in neocortical intrinsically bursting neurons.
The ionic mechanisms underlying the termination of action-potential (AP) bursts and postburst afterhyperpolarization (AHP) in intrinsically bursting (IB) neocortical neurons were investigated by performing intracellular recordings in thin slices of rat sensorimotor cortex. The blockade of Ca(2+)-activated K(+) currents enhanced postburst depolarizing afterpotentials, but had inconsistent and mi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1984
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.84.6.861